产品货号:
Z33122
中文名称:
Alpha A Crystallin/CRYAA抗体
英文名称:
Anti-Alpha A Crystallin/CRYAA Antibody (Clone#10B9)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Alpha A Crystallin/CRYAA Antibody (Clone#10B9) |
指标别名 | CRYAA;Acry 1;CRYA 1;CRYA1;CRYAA;Crystallin alpha 1;Crystallin alpha A;HSPB 4 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,ICC/IF |
基因名称 | CRYAA |
克隆号 | 10B9 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | E.coli-derived human Alpha A Crystallin recombinant protein (Position:M1-S173).Human Alpha A Crystallin shares 94.8% amino acid (aa) sequence identity with both mouse and rat Alpha A Crystallin. |
实际分子量 | 17KD/20KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | protein G purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Alpha-crystallin A chain is a protein that in humans is encoded by the CRYAA gene.Mammalian lens crystallins are divided into alpha,beta,and gamma families.Alpha crystallins are composed of two gene products:alpha-A and alpha-B,for acidic and basic,respectively.Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family.They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone;instead they hold them in large soluble aggregates.Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture.The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions.Alpha-A and alpha-B gene products are differentially expressed;alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs.Defects in this gene cause autosomal dominant congenital cataract (ADCC). |
Uniprot ID | P02489 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for ICC. |
基因名全称 | crystallin alpha A |
蛋白名全称 | Alpha-crystallin A chain |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400 |
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